Second Stage Theater, a leading nonprofit that presents work by living American writers both on and off Broadway, is giving up its Rem Koolhaas-designed Off Broadway home in a former bank near Times Square, saying its rent was too high and its lease had unfavorable terms. The theater company, which has nurtured multiple Pulitzer Prize- and Tony Award-winning shows over the years, until recently operated three theaters: the Hayes Theater on Broadway, an Off Off Broadway space on the Upper West Side and an Off Broadway theater, the Tony Kiser Theater, in a former bank building at the corner of West 43rd Street and Eighth Avenue. Last year, Second Stage gave up the lease on its Off Off Broadway space. www.2st.com